The Merseyside giants have got the better of Norwich City and Southampton, while the Gunners have fought their way to narrow victories over Newcastle United and Burnley.
There will now be a desire to maintain an advantage in the title race, with Manchester City, Tottenham Hotspur, Manchester United and Chelsea having already dropped points.
Here, Sports Mole predicts how Liverpool could line up for the showdown at Anfield.
Ahead of the match with Southampton last weekend, Jurgen Klopp had to contemplate rotating his players as a result of the UEFA Super Cup final with Chelsea less than 72 hours earlier.
However, having had a week of preparation in the North-West, Klopp will name what he regards to be his best possible XI for this game.