The Terriers, already relegated to the Championship, have lost 14 games in a row and have not registered a point since their 0-0 draw with Cardiff City in January.
A Champions League spot for next season is still possible for Ole Gunnar Solskjaer's side, but it remains unlikely with three points separating them from fourth-placed Chelsea and a substantially lower goal difference. Nevertheless, victory is a must for United on Sunday to stay in the hunt heading into the final day.
Here, Sports Mole takes a look at how the Terriers could line up for Sunday's contest.
Huddersfield will stage a late fitness test for key midfielder Aaron Mooy after a hip injury has kept the Australian out of action for the last three games. It is unlikely that Ben Hamer and Laurent Depoitre will feature either due to recurrent knocks affecting both players.
Karlan Grant has shown potential for the Terriers this season, scoring a club-high four league goals in only 11 appearances since joining from Charlton Athletic in January.
Steve Mounie will likely lead the attack, providing an aerial threat for Huddersfield to play off.