NY Red Bulls vs. Inter Miami (Saturday, 11.00pm)
Playoff contenders New York Red Bulls host an Inter Miami side currently struggling near the foot of the MLS Eastern Conference on Saturday, at the Red Bull Arena.
While the home side are unbeaten in three and sit seventh in the standings, their Floridian counterparts come into the game on the back of five successive defeats.
We say: New York Red Bulls 2-0 Inter Miami
Though Miami are overdue to end their desperate losing run, the Red Bulls are a tough team to beat on their home patch and are unlikely to be unpicked by the visitors' toothless attack.
Therefore, the home side should stride on towards the playoffs, with Miami returning south with nothing to show for their efforts once again.
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Cincinnati vs. Philadelphia (Sunday, 1.00am)
Philadelphia Union's playoff position is far from secured with seven Major League Soccer games still to play, despite Jim Curtin's side sitting in third place in the Eastern Conference, they are only three points clear of the chasing pack.
FC Cincinnati are competing for pride now after a season of struggle, and they will be hopeful of lifting themselves off the bottom of the table as they have a game in hand on Toronto, who are directly above them in 13th spot.
We say: FC Cincinnati 0-3 Philadelphia Union
Philadelphia are strong favourites for this clash given their better league position and current run of form, and there should be no reason why they cannot put on another dominant display.
Cincinnati will want to keep improving under new manager Marshall, but Sunday's game against Union is going to be a tough task and the visitors' quality should shine through.
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Seattle vs. Vancouver (Sunday, 2.00am)
Western Conference leaders Seattle Sounders are aiming to remain on top with another three points at Lumen Field, where they will welcome playoff-chasing Vancouver Whitecaps on Sunday.
The Whitecaps are currently sitting in eighth place and are one point behind the playoff positions, but they do have a game in hand on sixth-placed Los Angeles Galaxy and fifth-placed Real Salt Lake, who are both just two points above Vancouver.
We say: Seattle Sounders 1-1 Vancouver Whitecaps
Vancouver will understand that Sunday's challenge is going to be a tough test, but if they are serious about reaching the playoffs, coming away with at least a point this weekend would be seen as a positive result.
Seattle are in good winning form; however, the Whitecaps are unbeaten in their last eight away league matches, suggesting that they have what it takes to get something from the game.
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