The Arizona Cardinals ended their nine-game losing streak with a 38-10 win over the Detroit Lions.

The Cardinals' defense returned to interception for touchdowns, Greg Toler completing a 102-yard run for the second.

Beanie Wells rushed for three touchdowns, his first in three weeks.

Mikel Leshore scored the Lions' only touchdown, as quarterback Matthew Stafford struggled with the throwing duties, completing 24 of 50 passes and throwing three interceptions.

Wideout Calvin Johnson received for 121 yards as he continues to try to break Jerry Rice's record for most receiving yards in a single season.

Neither side can make the playoffs, being ranked 14th and 15th in the NFC.