The Houston Rockets posted a sixth win in a row as they toppled the Toronto Raptors 107-95.
James Harden finished with 35 points – a 39th consecutive game in which he has scored 28 points or more – while Gerald Green added 18 off the bench.
Toronto's loss marked the end of a seven-game winning streak at home.
Defending champions the Golden State Warriors slumped to a 128-95 loss to the Boston Celtics.
Gordon Hayward had 30 points off the bench as Boston took control early on in the game, leading by 25 points at half-time.
Kyrie Irving added 19 points and 11 assists for the Celtics, who had started the game having lost five of six since the All-Star break.
JJ Redick had 19 of his 26 points in the first half as the Philadelphia 76ers beat the Orlando Magic 114-106.
The Sixers led for most of the game, but Orlando came to within a point late in the fourth quarter.
Jimmy Butler helped push Philadelphia ahead in the dying minutes, while Mike Scott sank a three-pointer to extend the advantage with 48.6 seconds remaining.
Meanwhile, the Indiana Pacers held off a strong second half from the Chicago Bulls to triumph 105-96.
The Bulls closed the gap after trailing by as much as 16 in the first half, before eventually falling short and recording their fifth loss in a row to the Pacers.
Elsewhere, Mike Conley recorded a career-high 40 points to help the Memphis Grizzlies edge the Portland Trail Blazers 120-111, while Karl-Anthony Towns led on 41 points as the Minnesota Timberwolves defeated the Oklahoma City Thunder 131-120.
