The Los Angeles Lakers made the perfect response to their dramatic midweek loss to the Orlando Magic, disposing of the Rockets 124-115 in Houston.
Although Houston started strongly to open up a seven-point lead after the first quarter, they ultimately were not able to fend off a 31-point explosion from LeBron James.
The 35-year-old veteran provided pivotal leadership down the stretch as he also finished with 12 assists and two steals.
The victory sees the Lakers, who were squeezed out 119-118 by Orlando on Thursday, extend their lead at the top of the Western Conference.
Having won four out of their previous five games, the Pelicans went into the clash desperate to give themselves the best chance at making it into the playoffs.
However their desire alone was not enough to compete with Leonard's 39-point performance.
Ben Simmons had eight assists to go along with his game-high 21 points.
The Milwaukee Bucks continued to assert themselves as the best team in the NBA, demolishing the Brooklyn Nets by 20 points.
Giannis Antetokounmpo finished with 29 points to help push the Bucks to more than seven games clear on top of the Eastern Conference standings.
There was a major upset in Boston as the Phoenix Suns pulled out a shock 123-119 win over the Celtics.
Not even a 43-point fourth quarter was enough to keep Boston from being handed just their fifth home loss this season.
The victory gives the Thunder some breathing room in the Western Conference from the eighth-placed Memphis Grizzlies.