The heavyweight contest between Tyson Fury and Alexander Ustinov has been cancelled after the Brit's uncle was admitted to hospital in a serious condition.
Fury had been due to face Dereck Chisora before the European titlist withdrew after fracturing his hand, but Ustinov, who had been sparring with Chisora, stepped in at late notice to take his place.
However, the bout, which was headlining the bill at the Phones4U Arena in Manchester, is off after Fury's uncle and former trainer, Hughie, became seriously ill overnight.
Frank Warren, who was promoting the show, said in a statement: "I'm very, very, disappointed for the fans. After Dereck Chisora pulled out because of his hand injury, we worked very hard to secure a world-ranked opponent in Ustinov.
"It's sad that his uncle Hughie is in a serious condition and our thoughts are with him."
The event will now be headlined by the European middleweight title match between Billy Joe Saunders and Emanuele Blandamura.