Northamptonshire have confirmed that Kyle Coetzer and Maurice Chambers will not be offered contracts for the 2016 season and beyond.
Batsman Coetzer, who was a part of the side that won the T20 Blast two years ago, joined the club in 2011, while bowler Chambers arrived from Essex in 2013.
"These are always difficult decisions to make regarding players' futures," head coach David Ripley told the club's official website.
"Kyle has been a model professional during his time here, he deals with success and failure in equal measure, a very valuable thing in a cricket dressing room. We wish him and his family well in the future.
"After a slow start in 2014, Maurice has put in a big effort this year but has been unable to get past our other seam bowlers and play regularly in the first team."
Northants finished fifth in the second division of the County Championship this year.