Primoz Roglic won the opening stage of the Vuelta a Espana as Chris Froome immediately dropped out of contention.

Froome, riding his final race for the Ineos Grenadiers, said on Monday he was unsure of his form coming into the Vuelta but got swift confirmation he was not in shape to contend for an eighth Grand Tour title as he was distanced on the first serious ramps of this 18-day race.

The 35-year-old lost the wheels late on the 173km stage from Irun to the Alto de Arrate above Eibar as the full impact of the career-threatening crash he suffered some 16 months ago was given another brutal illustration.

Ironically, it was an injection of pace from Froome's own team – working for Richard Carapaz – that did for the two-time Vuelta winner as he dropped out of the back of the peloton on the climb of the Alto de Elgeta, still 18km from home.

That left little hope Froome could get back on come the more challenging final climb of the Arrate, and he ended the day having conceded 11 minutes.

Froome said afterwards he will now ride in support of Carapaz, who took second on the stage.

"I got a bit caught out coming into the penultimate climb, I started pretty far back and got stuck behind a crash at the bottom," he said.

"I'm really happy to be here, I'm really, really happy to be racing a Grand Tour again after two years of not doing any Grand Tours and just going to take the race day by day and try and do as much for the team as I can.

"The sensations are good. I still miss a little bit of that top end from not having raced much but it's definitely an improvement and I hope to keep building throughout the race."

Instead the day belonged to Roglic, the defending champion who is desperate to make up for his disappointment at the Tour de France, where he lost the yellow jersey to fellow Slovenian Tadej Pogacar on the penultimate day last month.

This mountainous stage was an unusually brutal way to open a Grand Tour, but it had been intended as stage four following a planned start in Utrecht which fell victim to the pandemic.

And so instead it was straight on to the climbs, causing major splits amongst the overall contenders for red.

"It's a strange season so I'll just enjoy the leader's jersey, starting from tomorrow, and the fact that we're racing, hopefully it will be fun to watch at home."

With bonus seconds applied, Roglic takes a five-second lead over Carapaz and Martin third, a further two seconds back, while Carthy sits seventh with a 14-second deficit.

Enric Mas and Esteban Chaves also kept themselves in contention, 11 seconds down in the general classification.

But Dumoulin and Valverde are already a minute down while the likes of Thibaut Pinot and Aleksandr Vlasov suffered even greater deficits.