Arsenal attacker Leandro Trossard is absent from the Gunners' squad for Sunday's Premier League North London derby with Tottenham Hotspur due to injury.
The Belgian - who has netted in his last two appearances against Everton and PSV Eindhoven - was not pictured in training on Saturday, and the Gunners have confirmed that he is nursing a slight muscular problem.
With Gabriel Martinelli also out with a hamstring injury, Eddie Nketiah has been brought back into the starting lineup, which will seemingly push Gabriel Jesus out to the left-hand side.
Mikel Arteta has also demoted Kai Havertz back down the bench, as Fabio Vieira comes back into the midfield three, while David Raya makes his third successive start in goal over Aaron Ramsdale.
There is also a spot on the bench for Mohamed Elneny following his recovery from a knee injury, but Thomas Partey and Jurrien Timber remain out for the hosts.
Meanwhile, Tottenham boss Ange Posteocglou has made just the one change to his side from last weekend's win over Sheffield United, handing a full debut to Brennan Johnson at the tip of the attack.
Manor Solomon drops to the bench, where Richarlison is also present despite his game-winning cameo against the Blades, while Eric Dier and Alejo Veliz are among the visitors' replacements too.
Arsenal: Raya; White, Saliba, Gabriel, Zinchenko; Rice, Vieira, Odegaard; Saka, Nketiah, Jesus
Subs: Ramsdale, Cedric, Tomiyasu, Kiwior, Jorginho, Elneny, Smith Rowe, Nelson, Havertz
Tottenham Hotspur: Vicario; Porro, Romero, Van de Ven, Udogie; Sarr, Bissouma; Kulusevski, Maddison, Son; Johnson
Subs: Forster, Royal, Dier, Davies, Skipp, Hojbjerg, Solomon, Richarlison, Veliz