Everton vs. Aston Villa (Saturday, 3.00pm)
Seeking a third successive Premier League home win under the tutelage of Sean Dyche, Everton welcome Aston Villa to Goodison Park on Saturday afternoon.
The Toffees boosted their survival hopes with a 1-0 success over Leeds United last time out, while Unai Emery's men suffered a dramatic late 4-2 defeat to league leaders Arsenal.
We say: Everton 1-1 Aston Villa
With both of Everton's goals under Dyche so far coming from defenders, the Toffees' prolonged lack of threat in the final third will likely deny them a third successive home win, even if Villa's defending has left a lot to be desired recently.
In contrast, the Lions are proving consistently potent in the final third as Watkins continues his hot streak, but the Toffees defence can once again star for their side in a hard-fought draw.
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Leeds vs. Southampton (Saturday, 3.00pm)
A potentially pivotal relegation battle at the foot of the Premier League table takes place at Elland Road on Saturday as Leeds United play host to Southampton.
While the Saints are continuing with interim boss Ruben Selles for the time being, the Whites are set to have newly-appointed head coach Javi Gracia in the dugout for the first time, subject to obtaining a work permit.
We say: Leeds United 2-2 Southampton
The Elland Road faithful are sure to create a hostile atmosphere for Southampton while providing new boss Gracia with all the encouragement that he needs to get off to a flying start in the Leeds dugout.
Selles, meanwhile, will fancy his chances of guiding the Saints to another victory on Saturday, and although both sides are desperate to claim maximum points here, we feel that the spoils will be shared as they were six months ago at St Mary's.
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Leicester vs. Arsenal (Saturday, 3.00pm)
Arsenal can temporarily re-establish a five-point lead at the top of the Premier League table when they travel to meet Leicester City in Saturday's clash at the King Power.
The Foxes failed to make their first-half dominance count in a 3-0 loss to Manchester United last weekend, while the Gunners beat Aston Villa 4-2 in one of the games of the season.
We say: Leicester City 1-3 Arsenal
Having put four past Tottenham and created numerous chances in the first half against Man United, Leicester should have no trouble breaking down a shaky Arsenal backline even without Maddison, but the Gunners are the masters at overcoming adversity.
With Rodgers's side hardly watertight at the back either, an Arsenal crop with a taste for goals on the road can overcome any minor setbacks at the King Power to travel back to North London with another three points and an unassailable lead at the summit.
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> How Arsenal could line up against Leicester
> Arsenal injury, suspension list vs. Leicester City
West Ham vs. Nott'm Forest (Saturday, 3.00pm)
West Ham United will endeavour to climb out of the Premier League relegation zone when they welcome Nottingham Forest to the London Stadium on Saturday.
The Hammers currently sit 18th in the table, albeit just one point adrift of safety, while Forest are sitting five points clear of their opponents in 13th place.
We say: West Ham United 1-1 Nottingham Forest
While Nottingham Forest are not completely out of the relegation picture, the need to claim all three points is greater for a struggling West Ham side as they bid to climb out of the drop zone.
The Hammers will be regarded as slight favourites for Saturday's clash considering the respective home and away records of the two teams, but we believe that Forest will make life difficult for the hosts and force them to settle for a share of the spoils.
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Bournemouth vs. Man City (Saturday, 5.30pm)
Manchester City will be looking to bounce back from successive draws when they travel to the Vitality Stadium to face Bournemouth in the Premier League on Saturday evening.
The Citizens picked off the Cherries when the two teams met in the reverse fixture back in August, cruising to a 4-0 victory at the Etihad Stadium.
We say: Bournemouth 1-3 Manchester City
Failing to make the most of their dominance in possession has cost Man City in their last two games and on several other occasions over the years, and they can ill-afford to drop more points if they wish to keep in touch with title rivals Arsenal.
Facing a Bournemouth side who they have a flawless record against is seemingly the perfect fixture for them to bounce back, and while their backline could be tested by the Cherries, Guardiola's men should have too much strength for the hosts.
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> How Man City could line up against Bournemouth
> Man City injury, suspension list vs. Bournemouth
Crystal Palace vs. Liverpool (Saturday, 7.45pm)
The walking wounded of Liverpool return to Premier League action with glum faces as they prepare to take on Crystal Palace at Selhurst Park on Saturday evening.
The Reds were demolished 5-2 by Real Madrid in the first leg of their Champions League last-16 tie in midweek, while Patrick Vieira's men were cruelly pegged back in a 1-1 draw against Brentford.
We say: Crystal Palace 0-1 Liverpool
Luckily for Liverpool, they will not be tackling a prolific Real Madrid side every week, and facing a Crystal Palace team who just cannot get over the line spells hope for an immediate return to winning ways.
Vieira's men have proven resilient against some revered teams recently, but the lack of an out-and-out goalscorer in Zaha's absence is still bedevilling them, and we have faith in Liverpool to right the wrongs of Wednesday and extend their top-flight winning streak by the narrowest of margins.
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> How Liverpool could line up against Crystal Palace
> Liverpool injury, suspension list vs. Crystal Palace body check tags ::