Arsenal will be determined to get back on track after their mini dip in results this week, while Chelsea are continuing to push for fourth spot in the Premier League.
The two sides go head to head at the Emirates on Saturday with Arsene Wenger likely to rely on Robin van Persie for goals with the possibility of Alex Oxlade-Chamberlain providing support to the Dutchman.
With Mikel Arteta expected to be ruled out for the remainder of the season with an ankle injury, Aaron Ramsey could take the Spaniard's spot in midfield.
Chelsea could make changes up front following their 1-0 win over Barcelona in the first leg of the Champions League semi-final last night.
Fernando Torres could be recalled after failing to make the field from the bench against Barca yesterday, with Daniel Sturridge alongside the Spain international.
With David Luiz still on the injury list, John Terry and Gary Cahill should keep their partnership in defence.
Current form:
Arsenal: WWLWWL
Chelsea: WWWDWW
Possible lineups:
Arsenal: Szczesny; Gibbs, Koscielny, Vermaelen, Sagna; Song, Ramsey, Rosicky, Walcott; Oxlade-Chamberlain; Van Persie
Chelsea: Cech; Cole, Cahill, Terry, Bosingwa; Ramires, Essien, Lampard, Kalou; Sturridge, Torres
Sports Mole says: 2-2