The Englishman regularly deputised at right-back in the absence of Hector Bellerin early on in the season, but Maitland-Niles has struggled for consistent game time since the restart.
As well as alleged off-the-field problems, the arrival of Cedric Soares from Southampton has also seen Maitland-Niles fall further down the pecking order at the Emirates Stadium.
Now, The Athletic report that the 22-year-old has accepted that he will not be in Arteta's long-term plans and is keen to advance his career elsewhere.
Maitland-Niles has been with Arsenal since the age of six and has emerged into the Gunners first team alongside fellow academy graduates Bukayo Saka, Reiss Nelson, Eddie Nketiah and Joe Willock over the past few seasons.
The Englishman still has three years left to run on his current Arsenal deal, and he has turned out 96 times across all competitions for the Gunners since making his debut in 2014.