Aston Villa vs. Bournemouth (Saturday, 3.00pm)
Fresh from an astounding win over Liverpool to further their Premier League survival bid, Bournemouth head to the West Midlands to tackle Aston Villa on Saturday afternoon.
The Cherries got the better of their Merseyside adversaries 1-0 last weekend, while Unai Emery's men were pegged back in a 1-1 draw against West Ham United.
We say: Aston Villa 1-1 Bournemouth
While Bournemouth have struck six of their eight Premier League goals against Villa in the first half, the Lions have proven adept at bouncing back, netting all four of their own top-flight goals against the Cherries in the second 45.
A closely-fought draw could therefore be on the menu, with Bournemouth unlikely to keep out Emery's well-oiled goalscoring machine but proving a consistent threat in the final third themselves in recent weeks.
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Brentford vs. Leicester (Saturday, 3.00pm)
Seeking to climb into the top six of the Premier League, European hopefuls Brentford welcome relegation-threatened Leicester City to the Gtech Community Stadium on Saturday.
While the Bees are looking to extend their unbeaten home run in the top flight to 10 matches, the Foxes are hoping to avoid a third successive away defeat.
We say: Brentford 2-1 Leicester City
The momentum is with Brentford heading into Saturday's contest and Frank's men will be regarded as favourites to come out on top considering the form of both sides.
Leicester will be desperate to turn their fortunes around and enter the international break on a high by claiming a morale-boosting victory in the capital, but we believe that the Bees will put a sting in the tail of the Foxes and secure maximum points on home soil.
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Southampton vs. Spurs (Saturday, 3.00pm)
Two sides striving for three points for entirely different reasons meet at St Mary's on Saturday afternoon, as Southampton host Tottenham Hotspur in the Premier League.
Ruben Selles's basement-dwellers were put to the sword 2-0 by Brentford in midweek, while the Lilywhites most recently cruised past Nottingham Forest 3-1 last weekend.
We say: Southampton 0-1 Tottenham Hotspur
A continued lack of ruthlessness and midweek fatigue will no doubt work against Southampton versus their more esteemed counterparts, who are primed to snap their dampening run of away defeats on the South Coast.
With Conte's side not possessing the desired attacking formula on the road either, goals may be at a premium here, but a refreshed Lilywhites crop should boost their top-four chances at the expense of Southampton's survival hopes.
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> How Tottenham could line up against Southampton
> Tottenham injury, suspension list vs. Southampton
Wolves vs. Leeds (Saturday, 3.00pm)
Wolverhampton Wanderers and Leeds United will be looking to return to winning ways when they face off at Molineux in the Premier League on Saturday.
The hosts will be seeking revenge against the Whites after losing 2-1 at Elland Road on the opening day of the season back in August.
We say: Wolverhampton Wanderers 2-0 Leeds United
Both teams will view this fixtures as a must-win as they bid to move away from danger, and although Wolves have struggled in recent league meetings with Leeds, they will be regarded as favourites to claim maximum points at Molineux.
Leeds have picked up the joint-fewest points (six) away from home in the top flight so far this season, and they may struggle to break down the hosts' backline on Saturday.
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Chelsea vs. Everton (Saturday, 5.30pm)
Seeking to continue their recent revival with a fourth win on the bounce in all tournaments, Chelsea host Everton in Saturday evening's Premier League offering at Stamford Bridge.
The Blues ran out 3-1 winners versus Leicester City last weekend, while Sean Dyche's own team in blue put Brentford to the sword 1-0.
We say: Chelsea 2-0 Everton
A spate of 1-0 wins at Goodison has done little to remedy Everton's dismal record on the road, and Dyche's side could very well be plunged back into the relegation places by the close of play this weekend.
With Potter's abundance of talent now showcasing said talent domestically and continentally, the reinvigorated Blues can potentially leave the anonymity of 10th place behind with a straightforward success in the capital.
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> How Chelsea could line up against Everton
> Chelsea injury, suspension list vs. Leicester City body check tags ::