Chelsea vs. Burnley (Sunday, 12.00pm)
Thomas Tuchel will be looking for his first victory as Chelsea boss when the Blues welcome a revitalised Burnley to Stamford Bridge on Sunday afternoon.
The capital giants were held to a goalless draw by Wolverhampton Wanderers in Tuchel's first game in charge on Wednesday, while Burnley will enter this match off the back of a 3-2 win over Aston Villa.
We say: Chelsea 2-1 Burnley
Burnley are more than capable of pulling off a shock at Chelsea, having recorded a 1-0 win at Anfield in their last away league match. Tuchel has had time to work on the training ground in recent days, though, and we fancy the home side to edge a tight contest at Stamford Bridge.
Our tipster partners are predicting under 3.5 goals.
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> How Chelsea could line up against Burnley
> Chelsea injury, suspension list vs. Burnley
Leicester vs. Leeds (Sunday, 2.00pm)
Leicester City will be looking to maintain their good run of form and keep their Premier League title aspirations on course when they face Leeds United.
The Foxes head into the weekend's fixtures third in the division, two points behind leaders Manchester City, while Leeds are 12th after returning to winning ways in midweek.
We say: Leicester City 2-1 Leeds United
Even accounting for the draw with Everton last time out, Leicester enter this contest in fine form. Leeds, too, will be full of confidence after returning to winning ways in midweek.
The Foxes have won back-to-back games at the King Power Stadium and were comfortable winners the last time they faced United, so we are tipping them to prevail on Sunday afternoon.
Our tipster partners are predicting under 3.5 goals.
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West Ham vs. Liverpool (Sunday, 4.30pm)
Two teams separated by just one place and two points in the Premier League table will go head to head on Sunday when West Ham United welcome Liverpool to the London Stadium.
The in-form Hammers sit fifth following a fine run of form, while champions Liverpool go into the match in fourth place following their much-needed 3-1 victory at Tottenham Hotspur on Thursday night.
We say: West Ham United 1-2 Liverpool
West Ham come into this match in fine form, but their record against the traditional 'big six' this season is less impressive - two points from the 18 on offer.
Liverpool's victory over Tottenham on Thursday eases some of the pressure which was starting to build, and we expect them to follow that up with another triumph in the capital on Sunday.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
> How Liverpool could line up against West Ham
> Liverpool injury, suspension list vs. West Ham
Brighton vs. Spurs (Sunday, 7.15pm)
Tottenham Hotspur will be looking to return to winning ways in the Premier League when they travel to the Amex on Sunday evening to take on Brighton & Hove Albion.
Spurs suffered a 3-1 defeat at home to champions Liverpool on Thursday night, while Brighton will enter this weekend's contest off the back of a goalless draw with fellow strugglers Fulham.
We say: Brighton & Hove Albion 1-1 Tottenham Hotspur
Brighton have been the draw specialists in the Premier League this season, sharing the points on nine occasions, and we can see another draw in this contest. Kane's absence will hurt Tottenham, and we believe that Mourinho's side will drop more points at the Amex on Sunday night.
Our tipster partners are predicting a double chance bet on a home win or an away win.
> Click here to read our full preview for this match