Chelsea vs. Brighton (Wednesday, 7.30pm)
Chelsea will aim to keep the pressure on title-chasing Liverpool and Manchester City when they welcome Brighton & Hove Albion to Stamford Bridge on Wednesday.
The Blues marched to a 3-1 triumph over Aston Villa on Boxing Day, while Graham Potter's side eased to a 2-0 win over Brentford.
We say: Chelsea 2-1 Brighton & Hove Albion
Brighton certainly are a tough nut to crack away from home, and the Seagulls may feel that Wednesday provides the prime opportunity to end their barren scoreless run in this fixture.
Tuchel's side have been far from convincing at Stamford Bridge in recent weeks and continue to be bedevilled by fitness woes, but the bountiful options for change should help to settle a tight contest in Chelsea's favour.
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> How Chelsea could line up against Brighton
> Chelsea injury, suspension list vs. Brighton
Brentford vs. Man City (Wednesday, 8.15pm)
Following their involvement in a true Boxing Day classic, Manchester City resume their quest for Premier League glory during Wednesday's battle with Brentford.
The Bees went down 2-0 to Brighton & Hove Albion at the weekend, while Pep Guardiola's side came out on top in a nine-goal thriller with Leicester City.
We say: Brentford 1-3 Manchester City
Guardiola and City may very well have one eye on the impending showdown with Arsenal, but that should not impact their hopes of a routine win over an inconsistent Brentford.
The Bees have performed valiantly against the big teams on home soil, but amid an absentee crisis which is not letting up, City ought to record a 10th successive Premier League win in style.
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> How Man City could line up against Brentford
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