Tonight two of the biggest rivals in international football will meet at Wembley Stadium.
Not since 1999 have England and Scotland faced each other, when they contested a two-legged affair for the right to advance through to the European Championships that were jointly hosted by the Netherlands and Belgium.
In total, the two nations have met on 110 occasions and so Sports Mole has picked out five of the most memorable encounters.
1. England 9-3 Scotland, 1961
Jimmy Greaves showed just how clinical a centre-forward he was in this encounter by scoring a hat-trick. He was also well supported by his teammates Johnny Haynes and Bobby Smith, both of whom bagged braces. There was also time for the late Sir Bobby Robson and Bryan Douglas to get their names among the scorers.
Even the humiliated Scots claimed three goals courtesy of Dave Mackay, Davie Wilson and Pat Quinn on an eventful afternoon at Wembley.
2. England 2-3 Scotland, 1967
This encounter saw the World Champions humbled in their backyard just one year after they had lifted the famous trophy. Denis Law and Bobby Lennox put the away side in front, before Jack Charlton reduced the arrears.
Jim McCallion restored Scotland's two-goal advantage on his debut, meaning that Geoff Hurst's strike was a mere consolation.
3. England 1-2 Scotland, 1977
Gordon McQueen and Kenny Dalglish bagged the decisive goals for Scotland, but this match is largely remembered for what happened after the final whistle had been blown.
Thousands of Scotland fans, including Rod Stewart, broke onto the pitch and proceeded to tear up bits of turf and force the goalposts into collapsing.
4. England 2-0 Scotland, 1996
If ever there was a match that highlighted the natural talent that Paul Gascoigne had been blessed with, this was it. Prior to his moment of magic, Alan Shearer had put England ahead in this Euro 1996 group contest, before David Seaman saved a penalty from Scotland captain Gary McAllister.
After that, it was all about Gazza, who at the time played his club football for Glasgow Rangers.
He lifted the ball over a helpless Colin Hendry and with his very next touch he volleyed the ball beyond the reach of Andy Goram and into the net to seal the victory and maximum points for the Three Lions.
5. Scotland 0-2 England, 1999
Paul Scholes scored 14 goals in total for England, but he won't have made many more vital contributions for his country than this one at Hampden Park.
The former Manchester United midfielder scored twice before the break to give his nation a 2-0 advantage heading into the second leg at Wembley, which Scotland would win 1-0, meaning that England advanced to Euro 2000.
