Armenia vs. Romania (Wednesday, 5.00pm)
Armenia will be looking to maintain their perfect start to World Cup 2022 qualifying when they welcome Romania to the Republican Stadium on Wednesday evening.
Joaquin Caparros's side have defeated Liechtenstein and Iceland in their opening two Group J matches, while Romania have three points from a possible six.
We say: Armenia 1-1 Romania
Armenia have made a perfect start to their qualifying campaign and are unbeaten in seven matches.
Sunday's loss to Germany aside - a game in which Romania could have snatched a late point - the visitors have also been in good form.
That suggests this should be a tight match in Yerevan and we are backing this one to finish level.
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Lithuania vs. Italy (Wednesday, 7.45pm)
Aiming to seal maximum points from their opening three qualifiers for Qatar 2022, Italy travel to Vilnius on Wednesday to meet Lithuania.
While the hosts narrowly lost their opening match in Switzerland on Sunday, Roberto Mancini's ruthlessly efficient outfit brushed aside Bulgaria to make it two wins from two in Group C so far.
We say: Lithuania 0-2 Italy
Anything short of a third straight regulation victory for Italy would be a major surprise on Wednesday, as whichever combination of talent they choose to field has more than enough guile to unlock ultra-defensive opposition.
With a superb record in recent months, combined with their cold determination to put right the wrongs of the past World Cup qualifying campaign, the Azzurri can establish a hold on Group C's top spot that they may never relinquish.
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> How Italy could line up against Lithuania
N. Ireland vs. Bulgaria (Wednesday, 7.45pm)
After a slow start to World Cup Qualifying Group C for both nations, pointless pair Northern Ireland and Bulgaria meet in Belfast, on the back of lengthy winless streaks.
With the sides already trailing favourites Italy and Switzerland by six points, any continued hopes of a playoff place - even at this early stage - surely hinge on securing an overdue victory on Wednesday.
We say: Northern Ireland 1-0 Bulgaria
With both sides desperate for points to break the losing habit and keep them in with a long shot of a trip to the Middle East next year, this could be a tightly-contested affair.
Northern Ireland's chief problem has been in finding quality and composure in the final third, but their combination of vast experience and players hungry to impress on the international stage can just about see off a visiting side whose limitations have been exposed in the opening games of what could be an arduous campaign.
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Bosnia H'vina vs. France (Wednesday, 7.45pm)
Bosnia-Herzegovina are fighting an uphill battle to end a 10-game winless run when they welcome reigning world champions France to Sarajevo for their second match of World Cup Qualifying in Group D.
The hosts' inaugural game of qualification saw them play out a 2-2 draw with Finland, while France saw off Kazakhstan 2-0 to claim their first three points in Group D last time out.
We say: Bosnia-Herzegovina 0-2 France
Bosnia just cannot hack it home or away at the moment, but France boast a remarkable record on their travels and will be eyeing another positive result in Group D this week. Injuries to Martial and Kante should not affect Les Bleus' ability to get over the line in the Bosnian capital, so we can only predict a routine win for the reigning world champions to cement their position at the top of the group.
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> How France could line up against Bosnia
Ukraine vs. Kazakhstan (Wednesday, 7.45pm)
Ukraine will be looking to bounce back from their disappointing draw with Finland last weekend when they host Kazakhstan in their third World Cup 2022 qualifier on Wednesday.
Both sides have played against Group D leaders and current world champions France this month, with Andriy Shevchenko's men securing an impressive point, while Kazakhstan were beaten on home soil last Sunday.
We say: Ukraine 2-0 Kazakhstan
Ukraine have scored two or more goals in all of their previous four meetings against a Kazakhstan side who have conceded in five of their last seven international matches.
The hosts will be strong favourites for Wednesday's encounter and we can see them securing their first victory in Group D.
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Austria vs. Denmark (Wednesday, 7.45pm)
Group F's top two sides face off in World Cup 2022 qualifying on Wednesday evening as Austria welcome Denmark to the Ernst-Happel-Stadion.
The visitors have kicked off their qualifying campaign with victories over Israel and Moldova, while Austria drew with Scotland in their opener before seeing off the Faroe Islands.
We say: Austria 0-1 Denmark
Denmark have lost two of their last 25 matches in both friendly and competitive fixtures, while Austria have lost two of their last 18.
The visitors' form over the last six months in particular has been superb, especially in a defensive sense, and we cannot see past a Denmark victory in this clash between Group F's top two seeds.
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Moldova vs. Israel (Wednesday, 7.45pm)
Israel travel to Moldova for the first time since September 2008 when they face each other in their third World Cup 2022 qualifier on Wednesday evening.
The hosts head into this fixture deflated after conceding eight goals against Denmark on Sunday, while the visitors claimed their first point in Group D with a draw against Scotland.
We say: Moldova 0-1 Israel
The last four meetings between the two sides have seen both teams score but with Moldova finding the net only once in their last nine matches, we feel that the hosts may struggle to score on Wednesday.
Israel should have enough quality in the final third, with Dabbur and Zahavi leading the line, to secure a narrow victory at the Zimbru Stadium.
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Scotland vs. Faroe Islands (Wednesday, 7.45pm)
Scotland host the Faroe Islands on Wednesday evening in their third World Cup 2022 qualifier, as they bid to record their first victory in Group F.
Both sides have failed to win any of their last four international matches but a victory at Hampden Park for either team could potentially see them finish the international break inside the top two.
We say: Scotland 2-1 Faroe Islands
The Faroe Islands will fancy their chances of finding the net on Wednesday, having scored in nine of their last 10 international matches, while Scotland have conceded in each of their last five games.
Steve Clarke's men will still be the favourites heading into this clash and we expect them to secure a narrow victory at Hampden Park.
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Andorra vs. Hungary (Wednesday, 7.45pm)
Hungary travel to Andorra on Wednesday evening, where the two nations will face off in their third World Cup 2022 qualifier in Group I.
The visitors head into this fixture unbeaten in their last eight international matches, while Andorra are winless from their last 13 games.
We say: Andorra 0-4 Hungary
With Poland facing England in midweek, Hungary know that this fixture against Andorra is the perfect opportunity to claim three points and move closer to the top two positions in Group I.
Despite losing their last meeting with Andorra, we believe the visitors will be too strong for the hosts and they should have no problems in securing a commanding victory.
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England vs. Poland (Wednesday, 7.45pm)
England face their toughest assignment yet in World Cup Qualifying Group I when they welcome Poland to Wembley Stadium on matchday three this Wednesday.
Both teams eased to comfortable victories at the weekend, with the Three Lions cruising past Albania 2-0 while Poland eased to a 3-0 win over Andorra.
We say: England 2-1 Poland
Lewandowski's absence is a crushing blow for Poland, but his adversary Kane is firing on all cylinders and ready to inspire England to yet another win on home soil. The Three Lions cannot expect to cruise to victory at Wembley like they did against San Marino, and a change in formation from Southgate could have a big impact on the hosts' attacking prowess, but we are confident in England's ability to get the job done and maintain their perfect start to qualification.
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> How England could line up against Poland
San Marino vs. Albania (Wednesday, 7.45pm)
Albania will be looking to record their second victory of the World Cup Qualifying campaign on Wednesday when they travel to take on San Marino.
The hosts suffered heavy defeats to England and Hungary in the first two games of qualifying, while Albania lost to England after beating Andorra in the first game.
We say: San Marino 0-3 Albania
It is difficult to predict anything other than a comfortable victory for the visitors on Wednesday, given San Marino's lowly standing on the international stage.
Sadly, La Serenissima look weak in all areas of the pitch, and that should be exploited by an improving Albania side who will look to close the international break with six points from three games.
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Germany vs. N. Macedonia (Wednesday, 7.45pm)
Germany will be looking to make it three wins from three in World Cup 2022 qualifying when they welcome North Macedonia to the MSV-Arena in Duisburg on Wednesday evening.
Joachim Low's men have seen off Iceland and Romania without conceding in their first two Group J games, while North Macedonia have three points from the same number of matches.
We say: Germany 3-0 North Macedonia
Nine points from nine would have been Germany's target from these March fixtures and they are on course to achieve that.
North Macedonia will be in confident mood after brushing aside Liechtenstein at the weekend, but the hosts should have little trouble in getting the job done.
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> How Germany could line up against North Macedonia
Liechtenstein vs. Iceland (Wednesday, 7.45pm)
Struggling Iceland seek to end to a seven-match losing run as they visit Vaduz for their World Cup 2022 qualifying fixture against lowly Liechtenstein on Wednesday.
Arnar Vidarsson's first games in charge ended in losses to Germany and Armenia last week, in the opening stages of Iceland's Group J campaign, while the hosts went down to Euro 2020 finalists North Macedonia at the weekend.
We say: Liechtenstein 0-1 Iceland
Despite time catching up on several of their stars of successful past campaigns, Iceland have a handful of younger talents, such as Arnor Sigurdsson and Albert Gudmundsson, who are more than capable of ending their country's miserable recent run on Wednesday.
Disappointment at the start they have made upon the long road to Qatar is unlikely to be quelled by victory over minnows Liechtenstein, but it should at least relieve some of the pressure building on their new coach's shoulders.
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Greece vs. Georgia (Wednesday, 7.45pm)
Greece and Georgia will both be aiming to secure their first wins in World Cup Qualifying Group B when they do battle at the Toumba Stadium on Wednesday evening.
The hosts played out a 1-1 draw with Spain in their inaugural game of qualification, whereas Georgia have taken zero points from their first two matches in the group.
We say: Greece 1-0 Georgia
It has been nearly two years since Georgia last lost by a margin of two goals or more, and their narrow defeats to Sweden and Spain have embodied the fighting spirit with Sagnol's ranks. However, results are ultimately what matter and Greece have enjoyed plenty of positive ones over their midweek visitors down the years, and while this could be another close affair, we still expect the hosts to triumph.
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Spain vs. Kosovo (Wednesday, 7.45pm)
Spain will endeavour to keep the pressure on Sweden at the top of World Cup Qualifying Group B when they play host to Kosovo on matchday three this Wednesday.
Luis Enrique's men have taken four points from a possible six in the group so far, whereas Kosovo's opening match saw them suffer a 3-0 defeat to table-toppers Sweden at the weekend.
We say: Spain 3-0 Kosovo
Spain have not covered themselves in glory over the past two matches, but this game is the perfect opportunity for Enrique's side to show what they are all about and display their attacking qualities. Without two key players in Celina and Berisha, the visitors' hopes of a shock result here a slim to none - even with Spain flattering to deceive - so we can only back a resounding home win this week.
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> How Spain could line up against Kosovo body check tags ::