Cincinnati vs. Kansas (Saturday, 7.30pm)
High-flying FC Cincinnati will have a fifth straight Major League Soccer victory in their sights when they welcome Sporting Kansas City to TQL Stadium on Saturday evening.
The away side, on the other hand, will make the journey aiming to pick up consecutive victories for the first time this term and kick-start their league journey off the back of what has undoubtedly been a rough start.
We say: FC Cincinnati 2-1 Sporting Kansas City
Cincinnati are on a roll at the moment and will definitely take some stopping on Saturday.
While we can see Sporting Kansas City putting up a decent fight, we are leaning towards a win for the home side at the end of the 90 minutes.
> Major League Soccer preview: Cincinnati vs Kansas
Toronto vs. NY City (Saturday, 7.30pm)
Fresh off winning their first match of the 2025 MLS campaign last week, Toronto welcome New York City FC to BMO Field on Saturday.
An early goal last weekend enabled the Reds to defeat Real Salt Lake 1-0, moving them up to 14th in the Eastern Conference table, four points below the Pigeons for 10th, with the latter losing 2-0 to the New England Revolution.
We say: Toronto 2-1 New York City FC
The Reds' first victory of the year should give them plenty of confidence heading into this game, particularly given how disciplined they have been at the back in recent games.
Nothing is going all that well for the Pigeons right now, and we believe their struggles will continue this weekend as no one has stepped up for them in recent matches.
> Major League Soccer preview: Toronto vs NY City
NY Red Bulls vs. Montreal (Saturday, 9.30pm)
Two sides in need of a spark in their respective MLS campaigns square off on Saturday as the New York Red Bulls host CF Montreal at Red Bull Arena.
A 2-1 loss versus DC United dropped the Red Bulls into ninth in the Eastern Conference, while Le CFM are still winless on the year, drawing 0-0 with Orlando City a week ago.
We say: New York Red Bulls 1-1 CF Montreal
Neither side will enter this match feeling good about their recent performances, and we expect that to impact this match, which could see two teams being a little lacklustre in terms of quality.
> Major League Soccer preview: NY Red Bulls vs Montreal
Philadelphia vs. DC United (Saturday, 9.30pm)
Matchday 10 of the 2025 Major League Soccer campaign sees Philadelphia Union and DC United go head-to-head against each other at Subaru Park on Saturday evening.
Both teams head into this one off the back of respective victories last time out, with the home side running riot against Atlanta United while the visitors just about did enough to see off the New York Red Bulls.
We say: Philadelphia Union 3-1 DC United
Recent meetings between Saturday's opponents suggest a high-scoring affair, and we are expecting the game to pan out that way.
That said, we are also backing the home side to flex their muscle in front of goal once again en route to a relatively comfortable win.
> Major League Soccer preview: Philadelphia vs DC United
Orlando City vs. Atlanta (Sunday, 12.15am)
Atlanta United set out in search of their first away win of the 2025 Major League Soccer campaign when they journey to the Inter & Co Stadium to take on Orlando City on Sunday morning.
This will be the first meeting between the two sides since their playoff semi-final clash back in November when the Lions picked up a narrow 1-0 victory thanks to a first-half strike from Argentine forward Ramiro Enrique.
We say: Orlando City 2-1 Atlanta United
Atlanta United have struggled to get going this season and are in for a tough 90 minutes against a well-drilled Orlando City side who are unbeaten in their last six outings. That said, we predict Pareja's men will make the most of their home advantage and come away with the desired result this weekend.
> Major League Soccer preview: Orlando City vs Atlanta
Charlotte FC vs. New England (Sunday, 12.30am)
Charlotte FC will be looking to maintain their 100% home record in the new MLS campaign as they go head to head with New England Revolution on Sunday morning.
The Revs, meanwhile, journey to the Bank of America Stadium seeking to secure a third win on the spin for the first time since June 2024, having edged out Atlanta United and New York City FC in their previous two outings.
We say: Charlotte FC 2-0 New England Revolution
After stumbling into the season, New England Revolution appear to have hit their stride and will be looking to maintain their new-found form. However, Charlotte have made the Bank of America Stadium a tough ground for any visiting side and we fancy them to make it 10 consecutive league wins in front of their home supporters.
> Major League Soccer preview: Charlotte FC vs New England
Columbus Crew vs. Earthquakes (Sunday, 12.30am)
Columbus Crew will host San Jose Earthquakes at the Lower.com Field in their gameweek 10 MLS fixture this weekend.
The home side will be looking to get back to winning ways, after they saw their three-game winning streak ended by Inter Miami in their last outing, while the visitors will come into this contest off the back of consecutive losses.
We say: Columbus Crew 2-1 San Jose Earthquakes
Although Columbus Crew suffered a narrow loss to Inter Miami in their last league outing, the Crew still have a lot of quality to hurt the visitors, but given the visitors' need to turn their season around, they will be desperate for a favourable result; therefore, we predict a 2-1 win for the home team.
> Major League Soccer preview: Columbus Crew vs Earthquakes
San Diego vs. Salt Lake (Sunday, 12.30am)
Two sides looking to snap their run of two consecutive defeats square off in the MLS as San Diego FC play host to Real Salt Lake at the Snapdragon Stadium on Sunday morning.
This will be the second meeting between the two sides this season, after the hosts secured a 3-1 comeback victory at the America First Field on March 9 thanks to goals from Franco Negri, Anders Dreyer and Marcus Ingvartsen.
We say: San Diego 2-0 Real Salt Lake
Having enjoyed a solid start to their debut campaign, San Diego have seen their form water down in recent weeks and will be looking to bounce back on Sunday. Varas's men take on an out-of-sorts Real Salt Lake side and we are backing them to come out on top in front of their home supporters.
> Major League Soccer preview: San Diego vs Salt Lake
Houston vs. Austin (Sunday, 1.30am)
Houston Dynamo will clash against Austin FC at the Shell Energy Stadium in their MLS clash this weekend.
The hosts will be aiming to claim their first win in three games, while the visitors will be looking for back-to-back victories.
We say: Houston Dynamo 1-2 Austin FC
After their initial struggles in April, Austin FC have returned to winning ways, and up against second-bottom Houston, they are in line for a win, and we predict a 2-1 victory.
> Major League Soccer preview: Houston vs Austin
Nashville vs. Chicago Fire (Sunday, 1.30am)
Two teams separated by just a single point in the Eastern Conference of Major League Soccer will square off for the first time in 2025 on Saturday as Nashville SC welcome the Chicago Fire to GEODIS Park.
The Boys in Gold currently sit sixth in the East following a 3-0 loss to the Seattle Sounders, putting them just above the Fire who are eighth, with the latter suffering a 3-2 defeat versus FC Cincinnati.
We say: Nashville SC 1-0 Chicago Fire
Nashville have done a much better job this season of bouncing back after a rough outing, and we expect them to have their share of scoring opportunities against a side that have conceded multiple goals four times in 2025.
> Major League Soccer preview: Nashville vs Chicago Fire
Colorado vs. Seattle (Sunday, 2.30am)
The Seattle Sounders will be looking to secure a third straight win in the MLS this weekend, when they travel to Dick's Sporting Goods Park to face the Colorado Rapids.
The hosts are in fifth place in the Western Conference standings with 15 points after nine games, while the visitors are eighth with 12 points over the same period.
We say: Colorado Rapids 1-2 Seattle Sounders
While the Rapids have made a better start to the season, the Sounders are getting healthier and are starting to show the type of form that many expected from them at the start of the season.
We are expecting a close contest in Colorado this weekend, but feel that the visitors will be able to continue their upward trajectory by picking up another win in this one.
