Liverpool welcome closest rivals Manchester City to Anfield on Sunday in a showdown which could prove pivotal to this season's title race.
The Reds have dropped just two points in the Premier League this term and would move nine points clear of the defending champions if they make it 20 wins from their last 21 top-flight outings.
Liverpool have not kept a single clean sheet at home all season, though, which will be a concern heading into a match against the division's top scorers.
Here, Sports Mole rounds up the latest injury and suspension news for Jurgen Klopp's side ahead of the blockbuster contest.
Jordan Henderson
Status: Minor doubt
Type of injury: Illness
Possible return date: November 10 (vs. Man City)
Captain Jordan Henderson missed Tuesday night's Champions League win over Genk due to illness, but he is expected to have recovered in time for Sunday.
Xherdan Shaqiri
Status: Out
Type of injury: Calf
Possible return date: November 23 (vs. Crystal Palace)
Klopp is hopeful that Sunday's match will be the last that Shaqiri is forced to miss through his calf injury, with a return pencilled in for after the upcoming international break.
Joel Matip
Status: Out
Type of injury: Knee
Possible return date: November 23 (vs. Crystal Palace)
Matip will miss Sunday's showdown due to a knee injury he aggravated against Manchester United last month. A return after the international break is possible, although some reports have suggested that he could be sidelined until December.
Nathaniel Clyne
Status: Out
Type of injury: Knee
Possible return date: Unknown
Nathaniel Clyne is Liverpool's only long-term absentee, with a return not expected until next year after he suffered knee ligament damage in pre-season.
LIVERPOOL'S SUSPENSION LIST
Liverpool have no players suspended for this match.