Liverpool are missing Pepe Reina through illness, while Steven Gerrard and Martin Skrtel miss out with slight knocks.
Swansea City, after securing Premier League football in the debut season, are looking to finish in the top half of the table.
Brendan Rodgers starts with in-form forward Gylfi Sigurdsson and Danny Graham, with Scott Sinclair and Nathan Dyer on the flanks.
Kenny Dalglish pairs Andy Carroll with Luis Suarez up front, while Jonjo Shelvey starts in midfield with Jordan Henderson.
Swansea: Vorm, Rangel, Caulker, Williams, Taylor, Britton, Allen, Dyer, Sinclair, Sigurdsson, Graham
Liverpool: Doni, Kelly, Carragher, Agger, Johnson, Henderson, Shelvey, Maxi, Downing, Carroll, Suarez