Lorient came from a goal down to beat Brest thanks to second-half strikes from Bruno Ecuele-Manga and Kevin Monnet-Paquet.
Steeve Elana was alert in the Brest goal to save Arnold Mveumba's fifth-minute free-kick and the visitors took full advantage five minutes later.
Eden Ben Basat volleyed home sublimely after a superb through-ball from Bruno Grougi.
Lorient threatened just after the break when Alaixys Romao's header thumped off the upright.
However, the hosts were not to be denied and levelled in the 51st minute through Ecule-Manga, who flicked a head in at the near post.
Monnet-Paquet snatched victory for Lorient three minutes from time after latching onto Jeremie Aliadiere's cross.