The first Manchester derby of the season headlines gameweek 12 of the 2020-21 Premier League campaign as the two neighbours, separated by only one place and one point in the table, renew hostilities.
Joint-leaders Tottenham Hotspur and Liverpool both face away days in London against Crystal Palace and Fulham respectively on Sunday afternoon, while there is a Midlands clash between Wolverhampton Wanderers and Aston Villa on Saturday.
Just six points separate Sports Mole Editor Barney Corkhill and Football Editor Matt Law in our season-long predictions competition, which awards five points for the correct scoreline and two points for the correct result.
Click play below to watch or listen to their predictions for all 10 of this weekend's games.
Watch the full discussion here:
Or you can listen to the full podcast here:
FRIDAY
8pm - Leeds United vs. West Ham United (0:31)
SATURDAY
12.30pm - Wolves vs. Aston Villa (3:50)
3pm - Newcastle United vs. West Bromwich Albion (6:37)
5.30pm - Manchester United vs. Manchester City (9:47)
8pm - Everton vs. Chelsea (14:13)
SUNDAY
12pm - Southampton vs. Sheffield United (17:48)
2.15pm - Crystal Palace vs. Tottenham Hotspur (21:33)
4.30pm - Fulham vs. Liverpool (25:00)
7.15pm - Arsenal vs. Burnley (28:44)
7.15pm - Leicester City vs. Brighton & Hove Albion (32:55)