While the Spaniard has spoken about the difficulties of the club's recent schedule, City head into Sunday's fixture with minimal issues in the treatment room.
Here, Sports Mole rounds up all of Man City's latest injury and suspension news ahead of welcoming their neighbours to the Etihad Stadium.
Type of injury: Muscular
Possible return date: March 10 (vs. Southampton)
Ake is yet to make an appearance for Man City since the turn of the year, his last outing coming on Boxing Day. However, Guardiola revealed earlier this week that the Netherlands international was due to resume training on Wednesday.
MANCHESTER CITY'S SUSPENSION LIST
Man City have no players suspended for this game.