Arsenal
Out: None
Doubtful: Rob Holding (concussion)
Aston Villa
Out: Matty Cash (hamstring), Kortney Hause (ankle), Wesley (knee), Jack Grealish (shin)
Doubtful: None
Brighton & Hove Albion
Out: Florin Andone (knee), Solly March (knee), Adam Webster (ankle)
Doubtful: Tariq Lamptey (thigh)
Burnley
Out: Johann Berg Gudmundsson (hamstring), Ashley Barnes (thigh)
Doubtful: Chris Wood (hamstring), Erik Pieters (groin), Dale Stephens (knock), Robbie Brady (ankle), Jay Rodriguez (knock)
Chelsea
Out: Thiago Silva (muscle)
Doubtful: None
Crystal Palace
Out: James McArthur (unspecified), Connor Wickham (unspecified), Wilfried Zaha (thigh), Jeffrey Schlupp (thigh), Mamadou Sakho (thigh), Wayne Hennessey (unspecified), Nathan Ferguson (thigh), James Tomkins (eye), Nathaniel Clyne (muscle)
Doubtful: None
Everton
Out: Yerry Mina (calf), Jean-Philippe Gbamin (calf)
Doubtful: None
Fulham
Out: Tom Cairney (knee)
Doubtful: Aleksandar Mitrovic (unspecified)
Leeds United
Out: Kalvin Phillips (calf), Robin Koch (knee), Rodrigo Moreno (groin), Adam Forshaw (hip), Ian Poveda-Ocampo (ankle), Jamie Shackleton (abductor), Gaetano Berardo (knee)
Doubtful: Mateusz Klich (hip)
Leicester City
Out: James Justin (knee), Ayoze Perez (knee), Wesley Fofana (thigh), Dennis Praet (thigh), Wes Morgan (back), James Maddison (groin)
Doubtful: None
Liverpool
Out: Jordan Henderson (groin), Joel Matip (ankle), Joe Gomez (knee), Virgil van Dijk (knee)
Doubtful: Alisson Becker (personal), Diogo Jota (knee), Fabinho (muscle), James Milner (hamstring)
Manchester City
Out: Nathan Ake (muscle)
Doubtful: None
Manchester United
Out: Paul Pogba (thigh), Phil Jones (knee), Juan Mata (unspecified)
Doubtful: Edinson Cavani (muscle), Donny van de Beek (muscle), Scott McTominay (muscle), Daniel James (muscle)
Newcastle United
Out: Callum Wilson (hamstring), Javi Manquillo (ankle), Fabian Schar (knee)
Doubtful: Federico Fernandez (thigh), Joelinton (knock)
Sheffield United
Out: John Egan (foot), Sander Berge (thigh), Jack O'Connell (knee), Jack Robinson (unspecified), Lys Mousset (knock), Chris Basham (muscle), Jayden Bogle (leg), Jack Rodwell (unspecified)
Doubtful: None
Southampton
Out: Theo Walcott (thigh), Ibrahima Diallo (thigh), Kyle Walker-Peters (hamstring), Michael Obafemi (muscle), Oriol Romeu (ankle), William Smallbone (knee), Takumi Minamino (hamstring)
Doubtful: None
Tottenham Hotspur
Out: Giovani Lo Celso (thigh)
Doubtful: Serge Aurier (foot)
West Bromwich Albion
Out: Semi Ajayi (suspended), Robert Snodgrass (calf)
Doubtful: Kieran Gibbs (neck)
West Ham United
Out: Angelo Ogbonna (ankle), Andriy Yarmolenko (knee), Arthur Masuaku (knee)
Doubtful: Ryan Fredericks (groin)
Wolverhampton Wanderers
Out: Raul Jimenez (head), Willy Boly (thigh), Fernando Marcal (muscle), Daniel Podence (adductor)
Doubtful: None
