Southampton full-back Ryan Bertrand will miss his side's Premier League clash with Manchester United on Friday due to a knee injury.
The 27-year-old was also absent for the Saints' 1-1 draw with Watford on the opening day, and has not recovered in time to feature against the Red Devils.
Bertrand has not been in action since England's final group game at Euro 2016, but could return in time for next weekend's match against Sunderland.
Manager Claude Puel has no new injury concerns for the match and could hand Euro 2016 winner Jose Fonte his first start of the new season.
The match will be United's first competitive home game under new manager Jose Mourinho.
