Luke Shaw has suffered a suspected broken ankle during Manchester United's Champions League fixture with PSV Eindhoven.
The 20-year-old, who had enjoyed an excellent start to the season, was felled by PSV defender Hector Moreno after making a burst down the left flank.
The extent of the injury was immediately clear, and the England international was tended to by United's medical staff and paramedics for almost 10 minutes before being stretchered off the pitch.
Shaw, who was replaced by Marcos Rojo, had appeared in every United game this campaign.