Villa loanee Scott Sinclair scored for the first time since he found the net as a Swansea player in August 2012.
However, his goal could not stop new Villa boss Tim Sherwood losing his first game in charge of the club.
Visiting Stoke are unbeaten from their last five trips to Villa Park in the Premier League.
Chelsea 1-1 Burnley
Blues right-back Branislav Ivanovic scored for the fourth time in six appearances in all competitions.
Up the other end, Ben Mee's header was just the second goal from a corner that Chelsea have conceded this season.
The Clarets have won just two of their last 32 Premier League away matches, losing 24.
Crystal Palace 1-2 Arsenal
French international Olivier Giroud scored his 50th goal for Arsenal in all competitions.
It was also the striker's fifth goal in his last seven outings for the Gunners.
For hosting Palace, Glenn Murray found the net for the first time in the Premier League since May 2014.
Hull City 2-1 Queens Park Rangers
January signing Dame N'Doye has now scored two and assisted another two goals for the Tigers.
Meanwhile, QPR midfielder Joey Barton received the ninth red card of his career for hitting out at Tom Huddlestone.
Despite the defeat, Charlie Austin scored his 14th goal of the campaign for the R's.
Sunderland 0-0 West Bromwich Albion
The hosting Black Cats have drawn 13 of their 26 encounters this season, which is a Premier League record.
In fact, Sunderland have won just two of their last 15 matches at the Stadium of Light, losing six times.
West Brom have lost just one of the nine games that Tony Pulis has taken charge of.
Swansea City 2-1 Manchester United
Louis van Gaal's Man United conceded more than one goal in a game for the first time in 18 Premier League encounters.
Up the other end, Wayne Rooney recorded his first shot on target in the Premier League since the turn of the year.
The Swans have won three of their last four meetings against the Red Devils in all competitions.
Manchester City 5-0 Newcastle United
City playmaker David Silva took his Premier League goals tally to nine, which is his best return in a single season.
His two-goal contribution also helped City to record their first victory at the Etihad Stadium since January 4.
The Magpies have lost their last 11 Premier League meetings with the Citizens.
Tottenham Hotspur 2-2 West Ham United
Hosting Spurs have picked up 16 points from losing positions this season, which is more than any other Premier League club.
Harry Kane, who scored the stoppage-time equaliser, has fired in 24 goals in all competitions this season.
Meanwhile, the visiting Hammers have scored a Premier League-high 15 headed goals this term.
Everton 2-2 Leicester City
Despite the late equaliser, Everton are without a victory in front of their own supporters at Goodison Park since December 15.
Of Steven Naismith's last 11 goals, eight of them have been scored on Merseyside.
Romelu Lukaku had a total of nine shots against Leicester, but none of them were on target.
Southampton 0-2 Liverpool
The Reds have claimed 17 Premier League points in 2015, which is two more than any other club.
Up the other end of the pitch, Liverpool have kept five successive away clean sheets in the league for the first time since 1985.
The defeat means that the Saints have won just one of their last five matches in all competitions.
