Stuttgart's Ibrahima Traore was the first to create a chance, as he fired in a long-range effort which was kept out of the goalkeeper's bottom left corner with a smart save.
The visitors thought they had taken the lead in the 16th minute, but Konstantin Rausch's strike cannoned back off the crossbar with the keeper beaten.
Mike Frantz should have put Nuremberg ahead midway through the half as he glanced a header from close range wide of the left post.
The hosts doubled their lead after the interval when Drmic grabbed his brace after being picked out by a clever ball from Markus Feulner, leading his side to what could be a crucial win. body check tags ::