Vizela vs. Portimonense (Sunday, 3.30pm)
This will be the second meeting between the sides this season after the spoils were shared in an uneventful goalless draw back in September's reverse fixture.
We say: Vizela 1-1 Portimonense
Looking at past results between the sides, we can expect a cagey affair at the Estadio do FC Vizela on Sunday. We predict Vitoria de Guimaraes will frustrate the efforts of the hosts and hold out for a fourth draw on the trot.
Benfica vs. Guimaraes (Sunday, 6.00pm)
Vitoria de Guimaraes will be looking to avoid a third Primeira Liga defeat on the spin when they square off with Benfica at the Estadio do Sport Lisboa e Benfica on Sunday.
As Aguias, on the other hand, head into the game off the back of a thrilling Europa League draw with Ajax and will look to build on that performance and return to winning ways.
We say: Benfica 2-1 Vitoria de Guimaraes
Vitoria de Guimaraes have struggled to get going on the road this season, managing just one win from their last nine away games. Meanwhile, Benfica have been utterly dominant in the history of this fixture and considering their current fine form, we predict this trend will continue with As Aguias claiming all three points unscathed.
Estoril vs. Boavista (Sunday, 6.00pm)
The hosts, meanwhile, will be looking to quickly bounce back to winning ways after seeing their three-game unbeaten run come to an end against Sporting Lisbon last time out.
We say: Estoril Praia 1-2 Boavista
Winless in each of their last nine games in all competitions, Boavista head into Sunday's game in dire need of a morale-boosting win as they risk dropping into the relegation places. However, we predict they will take the positives from their fine display against Benfica and come away with all three points against a floundering Estoril Praia side.
Porto vs. Gil Vicente (Sunday, 8.30pm)
The Gilistas, who are unbeaten since the turn of the year, head into the game as one of the most in-form sides in the division and will look to keep the juggernaut rolling.
We say: Porto 2-1 Gil Vicente
Sunday's game sees two of the most in-form sides in the Portuguese Primeira Liga square off and this makes for an exciting watch. While we expect the Gilistas to push the hosts to the limit, we predict Porto will come away with all three points given they boast a significantly superior and more experienced crop of players.