Montenegro vs. Gibraltar (Saturday, 2.00pm)
Montenegro play host to Gibraltar on Saturday afternoon looking to make it back-to-back wins in Group G.
While the home side got their World Cup qualifying campaign off to the perfect start against Latvia, Gibraltar succumbed to Norway by a 3-0 scoreline.
We say: Montenegro 3-0 Gibraltar
Despite showing character against Norway, Gibraltar were fortunate to only lose by a 3-0 scoreline. With that in mind, we feel that Montenegro will make light work of the visitors, motivated to remain a fixture at the right end of the standings.
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Russia vs. Slovenia (Saturday, 2.00pm)
Russia and Slovenia square off on Saturday afternoon with the opportunity to record successive wins in Group H.
While Russia made hard work of their opening fixture against Malta, Slovenia posted a surprise 1-0 win over 2018 World Cup finalists Croatia.
We say: Russia 2-0 Slovenia
On the back of defeating Croatia, Slovenia will be full of confidence ahead of their visit to Sochi. Nevertheless, it may be difficult to replicate their performance from Wednesday evening, leading us to predict a comfortable triumph for the home side.
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Belarus vs. Estonia (Saturday, 5.00pm)
Estonia square off against Belarus on Saturday evening looking to respond to suffering a 6-2 defeat at the hands of Czech Republic.
With Group E only featuring five nations, Belarus warmed up for this contest with a 1-1 draw in a friendly against Honduras earlier this week.
We say: Belarus 2-1 Estonia
Having conceded six goals in the previous match, do not expect Estonia to throw caution to the wind during this contest. However, that may not help their cause, and we are backing the home side to edge this encounter by the odd goal in three.
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Norway vs. Turkey (Saturday, 5.00pm)
Norway and Turkey will be looking to build on winning starts to World Cup 2022 qualifying when they meet at Estadio La Rosaleda in Malaga on Saturday evening.
The fixture is being staged on neutral territory due to coronavirus travel restrictions, though Norway are the designated home team for this intriguing Group G clash.
We say: Norway 1-1 Turkey
Both teams have been tough to beat over the past couple of years and each are capable of producing big performances.
Turkey showed exactly what they are capable of with their win against the Netherlands and would likely welcome a point on Saturday, which we can see them earning.
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Netherlands vs. Latvia (Saturday, 5.00pm)
The Netherlands will aim to kickstart their World Cup Qualifying campaign at the second attempt when they welcome Latvia to the Johan Cruijff ArenA for their second match in Group G on Saturday.
Frank de Boer's men were put to the sword by Turkey in a six-goal thriller on Wednesday, while Latvia were no match for Montenegro in their inaugural game of qualification.
We say: Netherlands 3-0 Latvia
The Netherlands have often flattered to deceive under De Boer, and Latvia will be determined to take advantage of their defensive frailties as they eye a shock result. However, the visitors are yet to score against the Oranje and we cannot see that changing anytime soon - this should be a routine win for the Netherlands to kickstart their qualification campaign.
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> How the Netherlands could line up against Latvia
Croatia vs. Cyprus (Saturday, 5.00pm)
Aiming to bounce back from a shock defeat to Slovenia on matchday one, Croatia welcome Cyprus to the Stadion Rujevica for the second game of their World Cup Qualifying campaign in Group H.
Zlatko Dalic's side were nullified by Slovenia in a 1-0 defeat on Wednesday evening, while Cyprus took a point from their dull affair with Slovakia.
We say: Croatia 2-0 Cyprus
Cyprus can be encouraged by their performance against Slovakia, but attempting to get one over the 2018 finalists will likely be a step too far. Dalic will be demanding an immediate reaction from his side and has talented players waiting in the wings, so we can only back a win for the hosts on Saturday.
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Serbia vs. Portugal (Saturday, 7.45pm)
Serbia and Portugal will both be aiming to build on opening-day victories in World Cup qualification when they do battle at the Stadion Rajko Mitic on Saturday evening in Group A.
The hosts edged a five-goal thriller with the Republic of Ireland in their first game, while Portugal needed a huge stroke of luck to overcome Azerbaijan in midweek.
We say: Serbia 1-2 Portugal
Serbia's rearguard is there to be breached, but the quality that the hosts possess at the other end of the pitch is unquestionable. Portugal could and definitely should have scored more against Azerbaijan had Mahammadaliyev not played a blinder, and while Santos's men cannot expect to cruise to victory this weekend, we are backing the visitors to scrape a narrow win and leapfrog their opponents in the table.
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> How Portugal could line up against Serbia
Rep. Ireland vs. Luxembourg (Saturday, 7.45pm)
Republic of Ireland will look to bring an end to their winless start to life under boss Stephen Kenny when they host Luxembourg in a World Cup 2022 qualifier on Saturday night.
The Boys in Green fell to a 3-2 loss against Serbia in their opening Group A fixture on Wednesday, while Luxembourg went down 1-0 to Qatar in a friendly on the same day.
We say: Republic of Ireland 2-0 Luxembourg
It would not be overstating it to label this a must-win game for Republic of Ireland, who are without a win in 10 games, nine of those under Kenny.
Luxembourg enjoyed a positive Nations League campaign and will be looking to nick a point in Dublin, but we are backing the hosts to pick up a maiden Group A victory.
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Czech Republic vs. Belgium (Saturday, 7.45pm)
Both Czech Republic and Belgium will be looking to make it back-to-back wins at the start of their 2022 World Cup qualifying campaigns when they lock horns in Prague on Saturday night.
Czech Republic opened their Group E challenge with a 6-2 victory away to Estonia on Thursday, while Belgium recorded a 3-1 win over Wales on the same night.
We say: Czech Republic 1-2 Belgium
Czech Republic are a team to be taken extremely seriously at this level of football, and they are more than capable of beating Belgium on Saturday to keep hold of first spot in Group E. Martinez's side have so much quality, though, and we are finding it difficult to back against them in Prague.
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Slovakia vs. Malta (Saturday, 7.45pm)
Slovakia will be looking to secure their first three points in Group H when they continue their 2022 World Cup qualification campaign at home to Malta on Saturday night.
Stefan Tarkovic's side will enter the match off the back of a goalless draw with Cyprus on Thursday, while Malta suffered a 3-1 loss to Russia in their group opener on the same night.
We say: Slovakia 1-0 Malta
Malta are an improving team, with their performance against Russia on Thursday an example of their progress. Slovakia will be the favourites to triumph on Saturday, and we are expecting a home victory, but it should be a tight and cagey affair in Trnava.
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