Kansas vs. Los Angeles (Saturday, 10.30pm)
Los Angeles FC will hope to climb into a playoff position in the Western Conference on Saturday when they travel to Children's Mercy Park for a matinee affair against Sporting Kansas City.
The Black and Gold are unbeaten in their last two matches since the international break, while the Wizards remain in second place in the Western Conference after a comprehensive 3-1 victory over the Colorado Rapids.
We say: Sporting Kansas City 2-2 Los Angeles FC
These sides have only faced each other four times in the regular season, with each team scoring at least once in all but one of those encounters.
These are two evenly matched teams with a strong attacking presence, but KC have conceded in five straight matches, while LA have given up at least a goal in three of their last four encounters.
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Toronto vs. Cincinnati (Sunday, 12.00am)
Toronto and FC Cincinnati square off on Sunday, as both sides look to bounce back after disappointing starts to the Major League Soccer campaign.
Toronto suffered a disappointing defeat to Nashville SC last time out, while their opponents have a platform to build on after a win over 1-0 win over Chicago Fire on Thursday.
We say: Toronto 1-1 FC Cincinnati
Both sides should see this game as a great opportunity to record a much-needed win, and we see them sharing the points on this occasion.
While Toronto may boast more quality in their squad, several key absentees have hit them hard, yet we still see them breaking their losing run against a fairly weak Cincinnati side, despite their victory last time out.
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Salt Lake vs. Houston (Sunday, 1.00am)
The Houston Dynamo will try to claim their first road victory of this campaign when they pay a visit to Rio Tinto Stadium to face Real Salt Lake on Saturday.
The Dynamo kept their undefeated home record intact on Wednesday by drawing 2-2 with the Portland Timbers, while Salt Lake lost a heartbreaker 2-1 to the Seattle Sounders in midweek.
We say: Real Salt Lake 2-1 Houston Dynamo
The Dynamo have not been shut out all season, but they have only defeated Salt Lake twice in Utah in regular-season play, with their last victory coming in September 2016 by a score of 1-0.
Salt Lake have been digging deep throughout the year, but they have been able to get results, thanks to some outstanding individual performances which could make the difference in this one.
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Chicago Fire vs. Philadelphia (Sunday, 1.00am)
The Philadelphia Union will try to extend their regular-season unbeaten run to eight games when they travel to Soldier Field on Saturday to face the Chicago Fire.
Philly are one of the hottest teams in the league, winning four of their last five matches, while the Fire are at the bottom of the Eastern Conference standings after losing 1-0 to FC Cincinnati on Wednesday.
We say: Chicago Fire 0-3 Philadelphia Union
The Fire have failed to score in six of their last seven matches and have lost three in a row, failing to find a goal against four teams who are currently outside of the playoff picture.
Philly have maintained six clean sheets this year, three of which have come away from home, including defeating Chicago 2-0 at Soldier Field back on May 8.
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Nashville vs. Montreal (Sunday, 1.30am)
Nashville SC will attempt to win back-to-back games for the first time this season when they host CF Montreal on Saturday at Nissan Stadium.
On Wednesday, an injury-time goal helped Nashville win for the first time in their last three matches, while Montreal are unbeaten in their previous two contests after playing to a 0-0 draw on Wednesday with DC United.
We say: Nashville SC 1-1 CF Montreal
These sides have met once this season, with Nashville erasing a two-goal deficit to draw 2-2, so there is some familiarity between these teams, who both have a defensive-minded approach.
Montreal have only allowed nine shots on target in their last three road matches, so expect the chances to be at a premium between two teams who are separated by only two points in the Eastern Conference table.
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Seattle vs. Vancouver (Sunday, 2.00am)
The Seattle Sounders will renew their rivalry with the Vancouver Whitecaps at Lumen Field on Saturday as the MLS leaders look to remain the only undefeated team this season.
Seattle won their second straight match 2-1 on Wednesday thanks to a late penalty kick, while the Caps conceded another injury-time goal in their last fixtures, falling 2-1 to the LA Galaxy for their fifth successive defeat.
We say: Seattle Sounders 2-0 Vancouver Whitecaps
The Sounders have won the last three meetings against the Caps by a combined score of 6-1, having not lost a home fixture to Vancouver since 2016.
Seattle continuously find ways to win, and their top attacking threat is at the top of his game, while the Caps keep finding ways to lose, and their top attacker appears to have lost his scoring touch.
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Earthquakes vs. LA Galaxy (Sunday, 3.00am)
San Jose Earthquakes will look to break a six-game winless run on Sunday, when they play host to Los Angeles Galaxy in Major League Soccer action.
Matias Almeyda's side will hope to bounce back from a 5-0 thrashing at the hands of Orlando City on Thursday, while their opponents narrowly beat Vancouver Whitecaps in their last outing.
We say: San Jose Earthquakes 0-2 Los Angeles Galaxy
Given the form of the two sides so far this season, we only see Sunday's clash going one way, with LA Galaxy expected to record a fairly comfortable win to extend their impressive start to the campaign.
The Earthquakes' defence looked weak in their recent thrashing at the hands of Orlando, and that could be exploited by a quality front line including Hernandez who has featured in 10 goals in nine MLS games so far this season.
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Portland vs. Minnesota Utd (Sunday, 4.00am)
Minnesota United will look to extend their unbeaten run to six Major League Soccer games on Sunday, when they travel to take on Portland Timbers.
The hosts picked up a point in a 2-2 draw with Houston Dynamo last time out, while Minnesota extended their strong run of form with a 2-0 win over Austin FC on Thursday.
We say: Portland Timbers 1-1 Minnesota United
While the start of the MLS campaign may point towards a Portland Timbers win, their visitors have improved hugely in their last five games and come into Sunday's clash with plenty of momentum.
We see them earning another creditable point in a draw between two sides on a fairly level playing field considering all of the factors at play.
