Tottenham Hotspur have confirmed that they will host at least two NFL matches per year at their new stadium.
Spurs, who are due to move into their 61,000-capacity ground in 2018, have agreed a 10-year partnership with the NFL.
Tottenham's new home will feature "a retractable grass pitch with an artificial surface underneath to be used for NFL games".
"We have an opportunity now to deliver one of the most unique sports, leisure and entertainment venues in the world," chairman Daniel Levy told the club's official website.
"We have a compelling and exciting partnership that will play its part as we begin transforming this area of Tottenham."
Spurs get their 2015-16 Premier League campaign underway with a trip to Manchester United on August 8.