Brighton & Hove Albion are the latest side attempting to end Tottenham Hotspur's perfect record at their new ground as they make the trip to North London on Tuesday evening.
Spurs have played three and won three at the Tottenham Hotspur Stadium, scoring seven goals and conceding none against Crystal Palace, Manchester City and Huddersfield Town.
The Lilywhites may have lost back-to-back matches in all competitions, but they are very much on a high ahead of Brighton's visit after booking a place in the Champions League semi-finals last Wednesday.
Here, Sports Mole looks at how Mauricio Pochettino's side could line up in midweek.
Out: Serge Aurier (hamstring), Harry Kane (ankle), Moussa Sissoko (groin)
Doubtful: Harry Winks (groin), Erik Lamela (hamstring), Hugo Lloris (muscle)
> Click here for Tottenham's latest injury and suspension news ahead of this match
Lloris missed Saturday's 1-0 defeat to Manchester City with a slight injury problem, meaning a third league start of the season for Paulo Gazzaniga.
With the first leg of their Champions League semi-final against Ajax a little over a week away, it is unlikely that Spurs will take any risks on their skipper's fitness.
Gazzaniga for Lloris was one of five changes made by Pochettino for his side's third meeting with City in 11 days. Both full-backs were also rotated, while Sissoko and Victor Wanyama dropped out.
Wanyama, Kieran Trippier and Danny Rose are all pushing for recalls, but Sissoko is unlikely to play again for a couple of weeks because of a groin injury.
Tottenham, despite the absence of top scorer Kane, have plenty of different options up top as Son Heung-min, Lucas Moura - a hat-trick scorer in Spurs' last home match - and Fernando Llorente can all play in that position.