Defending champion Emma Raducanu has been handed a first-round meeting with Alize Cornet at the US Open.
The 19-year-old, who made history in coming through qualifying to win the title in New York last year, is looking for a sustained return to form at Flushing Meadows.
However, Raducanu faces an opponent with a history of causing surprises at Grand Slams, her latest feat coming at Wimbledon as she ended the long undefeated streak of world number Iga Swiatek.
If Raducanu comes through that contest, either Taylor Townsend or Katerina Siniakova will await in the last 64, with Naomi Osaka and Danielle Collins also lurking in that eighth of the draw.
Meanwhile, Harriet Dart has been presented with the challenge of playing 10th seed Daria Kasatkina in her third appearance in the tournament.
On the men's side, Cameron Norrie, the seventh seed, will go up against Benoit Paire, and the left-hander has been placed in the same quarter as Rafael Nadal.
Former champion Andy Murray plays Argentina's Francisco Cerundolo with Matteo Berrettini a potential third-round opponent.
Young British representative Jack Draper, who may break into the top 50 of the world rankings by the end of the week, goes up against Finland's Emil Ruusuvuori.
Dan Evans meets Czech Republic's Jiri Vesely, while Kyle Edmund has been handed a meeting with French Open runner-up and fifth seed Casper Ruud.
