Novak Djokovic surged into the fourth round at Wimbledon while a couple more obstacles on his path to the final were removed.
Defending champion Djokovic dropped a set against Poland's Hubert Hurkacz on Court One but still went through 7-5 6-7 (5) 6-1 6-4, and will face Frenchman Ugo Humbert next.
"Credit to Hurkacz for playing well. He pushed me. He served well. He attacked the ball mid-court. He gave it all and played a great quality match, I thought," said Djokovic.
"I think I should have capitalised on my opportunities also in the second set. I wasn't really on top of his second serve. I was a bit hesitant in the play, which wasn't the case in the first two matches.
"But I think third set was great. The fourth set, as well, very solid. I'm really pleased with the way I finished the match."
Meanwhile fourth seed Kevin Anderson, beaten by Djokovic in the final 12 months ago and a potential semi-final opponent this year, was sent tumbling out.
Khachanov lost to Roberto Bautista Agut, the Spanish 23rd seed winning 6-3 7-6 (3) 6-1 to set up a manic Monday meeting with Benoit Paire.
The 11th seed also fell by the wayside, Russian Daniil Medvedev losing a three-and-a-half hour five-setter to Belgium's David Goffin.
He will face veteran Spaniard Fernando Verdasco, who beat Italy's Thomas Fabbiano in straight sets.
Humbert secured a shot at Djokovic after knocking out another seed, teenager Felix Auger-Aliassime, in straight sets.
