Estudiantes vs. Oriente (Wednesday, 11.00pm)
Estudiantes will be aiming to extend their unbeaten streak in the Copa Sudamericana when they host already-eliminated Oriente Petrolero at Estadio Jorge Luis Hirschi on Wednesday evening.
The hosts are battling Red Bull Bragantino of Brazil for top spot in Group C with one match left to play, while their Bolivian visitors are searching for their first points in the section.
We say: Estudiantes 4-1 Oriente Petrolero
Estudiantes have already secured their spot in the knockout stages of the Sudamericana but should view this match as the perfect opportunity to get back to winning ways after recent struggles in their domestic league.
Oriente only have pride to play for on Wednesday night, but we envisage that motivation not being enough for the visitors to avoid a heavy defeat in Buenos Aires.
> Click here to read our full preview for this match
Bragantino vs. Tacuary (Wednesday, 11.00pm)
Bragantino will be looking to preserve their first-placed standing in Group C of the Copa Sudamericana when they welcome Tacuary to Estadio Nabi Abi Chedid on Wednesday night.
The hosts are currently unbeaten in the section and have secured their spot in the knockout stages, while their Paraguayan visitors already know their journey in the competition will come to an end in Sao Paulo.
We say: Bragantino 2-0 Tacuary
Bragantino are already assured of a spot in the knockout stages, but they will be determined to finish top of the pile in Group C ahead of Estudiantes.
Tacuary will look to end their Sudamericana campaign with a shock result on Wednesday, although we believe the Paraguayans will come away from Sao Paulo empty handed.
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Emelec vs. Danubio (Thursday, 1.00am)
Emelec and Danubio will both be targeting a place in the Copa Sudamericana knockout rounds when they face off on Wednesday.
The Ecuadorian hosts head into the final group game in third position, while Danubio are a point better off in second place.
We say: Emelec 2-1 Danubio
Emelec have been held to a draw in their last four competitive home games, and we think they will have to settle for another point when they face Danubio in their final group match.
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Guarani vs. Huracan (Thursday, 1.00am)
Group leaders Club Guarani will look to book their place in the Copa Sudamericana knockout rounds when they play host to Huracan on Wednesday.
The visitors, meanwhile, are sitting in fourth position with five points to their name, but they still have an outside chance of finishing in second place.
We say: Guarani 2-0 Huracan
Guarani are unbeaten at home in this season's Copa Sudamericana, and we think they will maintain that impressive record when they face Huracan, who have lost 10 of their last 11 away games in all competitions.
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Santa Fe vs. Goias (Thursday, 3.00am)
There is everything to play for in Group G of the Copa Sudamericana on Thursday night when Santa Fe and Goias meet at the Estadio El Campin.
The hosts cannot afford to lose if they want to earn a place in the next stage of the competition, while a draw will be sufficient for the visitors.
We say: Santa Fe 0-1 Goias
It might be a must-not-lose match for Santa Fe, but the defensive abilities of Goias are likely going to be too much for them to break down in this one.
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Universitario vs. Gimnasia (Thursday, 3.00am)
Universitario will attempt to progress to the knockout rounds of the Copa Sudamericana when they welcome Gimnasia to Estadio Monumental on Wednesday.
While the hosts occupy second place in the group, Gimnasia sit in fourth position but still have an outside chance to climb into the top two.
We say: Universitario 1-0 Gimnasia
Gimnasia have never won an away game in the Copa Sudamericana, and we think their wait will continue after Wednesday's encounter because we expect the hosts to make full use of home advantage and replicate the 1-0 victory they picked up in the reverse fixture.
