Blackpool are missing Thomas Ince who begins a two-match suspension for making an offensive gesture to a match official during Monday's Capital One Cup defeat at Preston North End.
Midfielder Angel Martinez sits out through injury but Craig Cathcart starts after missing training during the week.
Michael Chopra starts his first league game for Barnsley, while Jack Robinson makes his home debut.
Dale Jennings is suspended for the visitors after his red card last weekend against Wigan Athletic and Kelvin Etuhu is ruled out through injury.
Blackpool:: Gilks, Broadfoot, MacKenzie, Cathcart, Robinson, Basham, Ferguson, Osbourne, Grant, Davies, Chopra
Barnsley:: Steele, Wiseman, Mvoto, Golbourne, O'Brien, Digby, Dawson, Perkins, Cywka, O'Grady, Dagnall