These two teams are desperately seeking points for differing reasons, with Greuther Furth currently propping up the Bundesliga, sitting 11 points adrift of safety.
They will welcome RB Leipzig on Sunday, who are hoping to push themselves into a Champions League spot, which they are just outside of right now.
Match preview
Greuther Furth have found the season to be a difficult one so far, winning just three games throughout the campaign, which is why they find themselves bottom of the Bundesliga.
However, they may take some belief from the fact that all of those victories have taken place at home, which is where they will be on Sunday at the Stadion am Laubenweg.
They have managed to take points from their previous three games in front of their own fans, defeating both Mainz and Hertha Berlin, while they also drew with Koln.
However, in Greuther Furth's most recent outing they lost against VfL Bochum 2-1, where an own goal from Armel Bella-Kotchap almost brought them back into the game, but they were not able to hang on at 1-1.
That was only the second time the team have been defeated across their previous 10 outings, which showcases the fighting spirit that the squad are bringing to this relegation fight.
RB Leipzig enjoyed an unplanned midweek rest heading into this game due to CSKA Moscow no longer being involved in the Europa League, and that will have allowed the squad to rest and prepare for this match.
They are undefeated in their previous seven fixtures heading into this one, which should provide plenty of confidence to the group as they look to push up the table.
A victory on Sunday has the potential to take Leipzig into the top four, possibly leapfrogging Hoffenheim depending on the other result, which is something that they are hoping for.
Earlier this season the squad enjoyed a dominant victory against Greuther Furth, despite the fact they had to come back from behind, eventually winning 4-1.
However, Domenico Tedesco's team have struggled away from home in this campaign, that result being one of only three times they have taken three points on the road.
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Team News
The hosts are without Robin Kehr, Marius Funk and Jessic Ngankam, who are all dealing with long-term injuries, which has stretched the squad at times this season.
However, the club was able to welcome back Jeremy Dudziak in their previous game, which was a boost, although he was not fit enough to feature for the full 90 minutes.
Tedesco had been rotating things frequently for the visitors recently due to their high volume of matches, but after a break over the past week, he could opt to go for a similar team this time around.
Yussuf Poulsen and Christopher Nkunku are likely to retain their places up front, with their partnership being a crucial one for the club, while the only injury concern they had was Josko Gvardiol, who was able to return in the previous game.
Greuther Furth possible starting lineup:
Linde; Itter, Viergever, Griesbeck, Meyerhofer; Christiansen, Tillman, Seguin, Dudziak; Leweling, Hrgota
RB Leipzig possible starting lineup:
Gulacsi; Klostermann, Orban, Gvardiol; Mukiele, Kampl, Haidara, Tasende, Forsberg; Poulsen, Nkunku
We say: Greuther Furth 1-3 RB Leipzig
Greuther Furth are sure to put up a fight within this fixture, as that is something they have been displaying in all of their recent performances.
However, RB Leipzig should be able to edge this one due to the added quality that they have at their disposal, as the squad aims for a Champions League place.
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