Liverpool welcome Napoli to Anfield on Wednesday knowing that victory would secure top spot in Group E of the Champions League with a game to spare.
The holders are currently one point clear at the top of the pool and would open up an unassailable lead with a fourth successive European victory, while even a defeat could be enough to seal their place in the last 16 should Red Bull Salzburg fail to beat Genk.
Napoli can also qualify for the knockout stages with a win, though, and the Italian outfit are the only team to have beaten Liverpool inside 90 minutes this season courtesy of their triumph in the reverse fixture.
Here, Sports Mole looks at how Jurgen Klopp could set his side up as they bid to avenge that defeat in Naples.
Out: Nathaniel Clyne (knee)
Doubtful: Joel Matip (knee), Xherdan Shaqiri (calf)
> Click here for Liverpool's latest injury and suspension news ahead of this match
Mohamed Salah was an unused substitute during Saturday's 2-1 win at Crystal Palace, but Klopp confirmed after the match that the Egyptian winger will be ready to return from his ankle injury for this game.
Andrew Robertson also came through that game unscathed having been struggling with a similar problem, and both are expected to be named in the starting lineup for Wednesday's match.
Salah's return means that Alex Oxlade-Chamberlain will likely be displaced in the front three, although his tally of three goals from his last two Champions League games could be enough to earn him a midfield role.
Klopp could also consider other changes in that area of the field with James Milner, Adam Lallana and Naby Keita all pushing for starts, but Fabinho looks certain to retain his place given that he will miss Saturday's game against Brighton & Hove Albion through suspension.
Dejan Lovren is again expected to start ahead of Joe Gomez with Joel Matip likely to miss out once more due to a knee injury, while behind them Alisson Becker will hope that there is no need for a repeat of the heroics which rescued his side in the same fixture last season.
Xherdan Shaqiri could play some role as he continues his recovery from a calf injury, although he is unlikely to be thrown straight in from the start considering he has now been out for more than two months.
