Udinese manager Andrea Stramaccioni has named Luis Muriel and Cyril Thereau in his attack for their Serie A clash against Palermo.
The two forwards lead the line with top scorer and captain Antonio Di Natale missing out on a place in the squad.
The visitors have also made a change in their midfield, with Emmanuel Agyemang Badu starting ahead of Panagiotis Kone.
Meanwhile, Palermo have made one change to the team that pulled off a shock 2-0 win against AC Milan, as Eros Pisano comes in for Michel Morganella.
Palermo: Sorrentino, Munoz, Gonzalez, Andelkovic, Pisano, Barreto, Maresca, Bolzoni, Lazaar, Vazquez, Dybala
Udinese: Karnezis, Widme, Heurtaux, Danilo, Piris, Agyemang, Allan, Guilherme, Fernandes, Muriel, Thereau
