The Baltimore Ravens lost their third consecutive game in the NFL, but still secured their place in the post-season.
A 98-yard interception return by Chris Harris gave the Denver Broncos momentum heading in to half-time with a 17-0 lead.
Eric Decker led the Broncos charge, receiving for 133 yards and scoring a touchdown.
Dennis Pitta received two touchdowns in the fourth quarter to reduce the deficit, but the Broncos' lead was too great.
Despite losing 34-17, Baltimore are guaranteed at least a wildcard in to the playoffs, but are yet to secure the AFC North title.
The Broncos, who won their ninth game in a row, move up to second in the AFC conference.