Jacksonville Jaguars have moved to 2-5 in the AFC South after a rush of second-quarter points helped them to a narrow win against the Buffalo Bills at Wembley Stadium.

In the second match of the NFL International Series, the Bills took the lead in a cagey opening quarter as Dan Carpenter kicked a field goal from 31 yards.

However, the Jags edged ahead when Blake Bortles threw a 10-yard touchdown pass to Allen Robinson.

Jacksonville then punished a Buffalo mistake after Chris Clemons seized on a fumble and returned the ball to the endzone.

Moments later, Bills quarterback EJ Manuel gifted a pick six to Telvin Smith, who ran the ball back 26 yards to give the Jags their third score in two minutes.

The Jaguars continued to pile on the points as TJ Yeldon rushed for 28 yards and, despite a missed extra-point conversion from Jason Myers, the Floridians had raced into a 27-3 lead.

Buffalo managed to reduce the arrears before half time with a touchdown for Robert Woods and another Carpenter field goal, to get within two scores.

Carpenter then added another three points after a 91-yard drive, which left the Bills 11 points down.

The Bills then got within a score late on as Manuel threw long to Marcus Easley for a 58-yard touchdown pass and LeSean McCoy's two-point conversion put Buffalo within a field goal.

Jacksonville then fell behind as Bortles was picked off by Corey Graham, who returned for 44 yards and looked to have given the Bills a match-winning touchdown.

However, a late score from Allen Hurns proved decisive as Jacksonville picked up only their second win of the season.