England and India's first one-day international was called off because of rain at Chester-le-Street.
The tourists posted a score of 274-7 before England took to the crease, and the hosts made 27-2 from 7.2 overs before the disruption.
Parthiv Patel was the pick of the Indian batsmen as he hit 95 before being bowled by James Anderson, but he was earlier dropped on seven by Ben Stokes.
Virat Kohli was also impressive with the bat, making 55 off 73 balls, but succumbed to the bowling of Samit Patel.
England began slowly for their time at the crease, and Cook was soon out for 4 after edging the ball onto his own stumps.
Kieswetter was next out for 6, and it was Jonathan Trott [14] and Ian Bell [2] who were out in the middle when the rain descended.
The next ODI in the five-game series takes place on Tuesday at the Rose Bowl, Southampton.