National selector Geoff Miller has confirmed that bowler James Anderson has been rested for next month's tour of India.
The 29-year-old, who has taken more wickets than any other pace-bowler for England over the summer, has made way to give some of the country's younger talent the opportunity to experience international cricket.
"A number of injuries and a decision to omit James Anderson in line with our policy of sensibly managing player workloads give opportunities for other very talented players to continue to develop as international cricketers," Miller told the ECB website.
"This squad contains an exciting balance of experienced international cricketers along with some very talented younger players who can play the high quality limited-overs cricket needed to challenge India."
Anderson made his one-day debut for England in December 2002.