England need only 209 to take a 2-1 series lead against Pakistan after bowling the hosts out in the final over of the third one-day international in Sharjah.
After winning the toss and electing to bat, Pakistan openers Azhar Ali and Babar Azam started strongly, nudging the new-ball swing of David Willey and Reece Topley around the ground to keep the scoreboard ticking over.
The duo put on 45 for the first wicket before Azam (22) went in the 11th over with a top-edge to Adil Rashid in the deep off the bowling of Chris Woakes.
Three of Pakistan's wickets were run-outs and the first of those saw the end of Ali for 36 after he and Mohammad Hafeez had put on 47 for the second wicket.
Pakistan danger-man Hafeez hit two sixes on his way to 45 before he pulled a Willey delivery to Root in the deep, leaving Pakistan on 132-3 in the 30th over.
The top-order had put the hosts in a solid position, but the middle-order failed to build the innings as more confusion led to their demise.
Both Shoaib Malik (16) and Mohammad Rizwan (1) lost their wickets cheaply to run-outs and England were soon into the tail-end.
Debutant Zafar Gohar played eccentrically for his 15 off 15 balls and the unbeaten Wahab Riaz helped Pakistan past the 200-mark in the closing overs with a quickfire 33.
In a dramatic last over, Woakes collected his fourth wicket by bowling out Mohammad Irfan with the final delivery after twice having lbw dismissals against Wahab overturned.