Antonio Nocerino and Diego Lopez have reportedly been placed on the transfer list by AC Milan.
Both players have found themselves out of head coach Sinisa Mihajlovic's plans in recent weeks.
According to Correire della Sera, there is no way back for the pair at the San Siro, with the club having decided to sell them during next month's transfer window.
The report adds that goalkeeper Lopez has been the subject of interest from clubs in the Premier League, while midfielder Nocerino is a target of Genoa.
It is believed that Milan need to sell players before they can recruit any new faces.