John Coleman was furious with the dismissal of his goalkeeper Dimitar Evtimov for throwing a bottle back into the crowd in the 2-1 loss to Blackpool.
Blackpool captain Jay Spearing had hit the winner from the penalty spot in front of 1,800 Blackpool fans but during their celebrations, Evtimov threw a bottle back into the crowd which had been thrown on the pitch and referee Ross Joyce showed him a straight red card.
Coleman and Pool assistant Gary Brabin were also shown a yellow card in the dugout for arguing with each other.
Coleman said: "To throw a bottle onto the pitch is a criminal offence but it's our keeper who is punished. It's wrong and something the FA needs to look at.
"He looped it back, he didn't throw it violently and yet it's him who is sent off. I think the ref should have used some common sense, our keeper wasn't trying to endanger anyone, it was a human reaction and other fans could use it to benefit from it. There is no place for it in football.
"We are devastated but you don't always get what you deserve in football."
Coleman claimed the penalty should not have been awarded as he thought defender Callum Johnson touched the ball first during his challenge.
Coleman said: "Callum got a nick on the ball for the penalty, we didn't think it was a penalty and the referee seemed to think about it for a long time. It's two major decisions which have gone against us.
"I thought we were the better team. It has spoilt a good night as the game has then gone for us, down to 10 men."
The Seasiders took the lead through Matty Virtue in the fifth minute, firing home from 18 yards.
Stanley equalised when Middlesbrough loan striker Luke Armstrong found the bottom corner of the net after 23 minutes.
Sam Finley hit the crossbar for the Reds and then the game erupted in the 81st minute. Johnson was judged to have fouled Liam Feeney in the area and Spearing netted the penalty and in the commotion that followed referee Joyce showed Evtimov a straight red card for throwing the bottle back into the crowd.
Blackpool boss Terry McPhillips was delighted as his side boosted their play-off push with their first win in five games.
"It's a massive win for us," said McPhillips. "It was great derby, a great game for the neutral and the atmosphere was magnificent, it helped us.
"Accrington are a good side but I thought we just shaded it. We needed to show that fighting spirit after last Saturday's 4-0 loss to Bristol Rovers, that was a bad day at the office, and we did.
"I thought the sending off was harsh, I saw their keeper chuck an object into the crowd but it shouldn't have been on the pitch in the first place. However, the referee has to go by the rules of the game.
"The atmosphere was superb and you could see how much it meant to the players by them celebrating with the crowd after, we haven't had that enough recently.
"It was a really good occasion and I am just pleased we came through a tough game and shaded it."