Another win on Saturday would temporarily lift them above Tottenham Hotspur into third place, in addition to taking them as many as nine points clear in the race for Champions League places.
Here, Sports Mole looks at how the Blues could line up for the London derby.
The weekly question surrounding Chelsea's team news is who will start up front, and this weekend it looks set to be Eden Hazard in a false nine role once again.
Alvaro Morata is expected to be fit following a hamstring problem, but he has been heavily linked with a move away from Stamford Bridge and may not make the matchday squad, with Olivier Giroud the back-up striker against his former club.
Pedro and Willian were both on the scoresheet against Newcastle and so will hope to have done enough to keep their places, leaving wantaway winger Callum Hudson-Odoi to settle for a place on the bench once again.