Arsenal will be seeking redemption against Chelsea at Stamford Bridge on Tuesday, just a month after the Gunners suffered a disappointing 2-1 defeat at the hands of Frank Lampard's team in the reverse fixture.
The North London side have struggled away from home all season, securing just two victories, but face a Chelsea side that have suffered four home defeats this term already.
Mikel Arteta will be hoping for an instant reaction to Saturday's 1-1 draw with Sheffield United, with his side still only 10 points adrift of Tuesday's opponents.
Here, Sports Mole rounds up Arsenal's latest injury and suspension news ahead of the clash with the Blues, who sit fourth in the Premier League.
Status: Out
Type of injury: Knee
Possible return date: Unknown
Calum Chambers was just starting to work his way into the Arsenal team when suffered a cruel knee injury in the first half against Chelsea during Mikel Arteta's second game in charge. The versatile defender is now unlikely to return until next season.
Status: Minor doubt
Type of injury: Illness
Possible return date: January 21 (vs. Chelsea)
Sokratis Papastathopoulos has been a much improved figure under Arteta and was certainly missed against Sheffield United. The Greek defender remains a doubt for Tuesday, with Shkodran Mustafi ready to deputise.
Status: Out
Type of injury: Shoulder
Possible return date: Unknown
Kieran Tierney remains out following the shoulder injury he picked up against West Ham United in December. The Scotland international has impressed in small bursts since arriving from Celtic in the summer, but has managed just 11 appearances for the North London club.
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
Reiss Nelson looked set to start against the Blades before picking up a serious injury in training. In his post-match press conference following Saturday's game, Arteta confirmed the outlook for Nelson was not good, although there is no word on a return date as of yet.
Status: Minor doubt
Type of injury: Thigh
Possible return date: January 21 (vs. Chelsea)
Sead Kolasinac also missed out on Saturday, but could return for Tuesday and relieve Bukayo Saka of his temporary left-back duties. Kolasinac has been in and out of the team all season with injuries and will face a test ahead of kickoff.
ARSENAL'S SUSPENSION LIST
Return date: February 2 (vs. Burnley)
Pierre-Emerick Aubameyang will miss Arsenal's trip to Stamford Bridge as he continues to sit out through suspension after his sending-off against Crystal Palace. The Gunners struggled in front of goal against Sheffield United in the Gabonese international's absence.